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Clinical Trial

Dartmouth scientists Michael Heinz (left) and Nicholas Jacobson (center) led the first clinical trial of an AI-powered therapy chatbot and found that, on average, people with diagnosed mental disorders experienced a significant reduction in symptoms. People in the study interacted with the software, known as Therabot, through a smartphone app where they responded to prompts from the Therabot avatar (right) or initiated conversations when they needed to talk.

AI Therapist Matches Human Care in Groundbreaking Mental Health Trial

Categories Brain & Behavior, Social Sciences, Technology
Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Glioblastoma is one of the most aggressive cancers, as illustrated by these brain scans from a patient with glioblastoma at initial diagnosis (left) and the same patient with a recurrent tumor (right).

Drug found to more than double survival time for glioblastoma patients

Categories Brain & Behavior, Health
inhaler

Inhaled Gene Therapy Offers New Hope for Cystic Fibrosis Patients

Categories Health
“We wish to determine whether adding ketamine to existing treatment would terminate status epilepticus in more patients than the current treatment,” said neurologist Jaideep Kapur, MD, PhD, co-director of the University of Virginia’s Brain Institute and an epileptologist (epilepsy expert) at UVA Health and the UVA School of Medicine. “Our hope is that this trial can improve treatment guidelines for patients suffering from these dangerous seizures.”

Ketamine Could Be Game-Changer for Treating Life-Threatening Seizures

Categories Health
Man's hand reaches for a glass of alcohol. Conceptual image on the subject of alcoholism. Copy space for your text.

Popular Weight Loss Drug Shows Surprising Power to Curb Alcohol Cravings

Categories Brain & Behavior, Health
Primary Prevention trial participant Hannah Richardson, 24, undergoes a clinical exam given by WashU Medicine neurologist Nupur Ghoshal, MD, PhD. The international trial, led by WashU Medicine, aims to determine whether stopping the early molecular changes that lead to symptomatic Alzheimer’s disease can prevent the disease from ever taking hold.

Young Adults Join Battle Against Alzheimer’s in Historic Prevention Trial

Categories Brain & Behavior
Patient receiving a COVID-19 vaccination in their arm Credit: Steven Cornfield

New Therapeutic Vaccine Shows Promise in Clearing Precancerous Cervical Lesions

Categories Health
These 3D models illustrate the study's findings. The top left image shows a circular coil used for magnetic seizure therapy (MST), while the top right image shows unilateral electrode placement for electroconvulsive therapy (ECT). The bottom row displays simulated electric field distribution in the brain during stimulation for each method. Warmer colors (red) indicate stronger electric fields, while cooler colors (blue) represent weaker fields, highlighting differences in how each technique interacts with brain regions.

Magnetic Therapy Offers Breakthrough for Depression, Boosting Treatment Efficacy Without the Cognitive Costs

Categories Brain & Behavior
Ohio State logo

The staying power of bifocal contact lens benefits in young kids

Categories Technology
Neural stem cells, shown here, can be made to develop into the varied types of cells found in the nervous system.

Neural Stem Cell Advance Offers New Hope for Spinal Cord Injury Patients

Categories Brain & Behavior, Health
Volunteer and patient in trial

New Drug May Boost Brain Function in People with Down Syndrome

Categories Brain & Behavior
Person getting vaccinated

Revolutionary HIV Prevention: Twice-Yearly Injection Shows Near-Perfect Protection in Landmark Trial

Categories Health
Kristina Simonyan

New Med Shows Promise for Voice Disorder After Patient Reports Booze Effects

Categories Health
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