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cancer treatment

CD8 T cell priming occurs in two phases. In the activation phase (day 1), naïve T cells engage with dendritic cells (DC) for 24 hours, then detach, proliferate, and move deeper into the lymph node. In the selection phase (days 2-3), activated T cells regain sensitivity, re-engage with antigen-presenting cells, and receive IL-2 support from CD4 T cells. Regulatory T cells limit IL-2 availability, driving the expansion and differentiation of high-affinity CD8 T cells into effector cells.

Hidden Dance of T-Cells Reveals New Immune System Strategy Against Viruses

Categories Health

Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image by NIH

One Shot Wonder: New Drug Eliminates Large Breast Tumors with Single Dose

Categories Health

infographic of process involved in the liposomal treatment

Cancer Treatment Uses RNA to Restore Natural Tumor Fighting Balance

Categories Health

Grape-based compounds kill colon cancer stem cells in mice

Common Grape Compound Could Make Cancer Treatment More Effective

Categories Health

Example scan

New Scan Spots Drug-Resistant Cancer Before Treatment Starts

Categories Health, Technology

Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Glioblastoma is one of the most aggressive cancers, as illustrated by these brain scans from a patient with glioblastoma at initial diagnosis (left) and the same patient with a recurrent tumor (right).

Brain Tumors Hijack Body’s Clock to Fuel Growth

Categories Health

Left: Normal cervical cancer cells with well-formed nuclei in blue and well-organized, elongated actin filaments – which play an essential role in cell survival and division – in green. Right: destabilised cervical cancer cells after gold compound treatment show structural integrity compromised while the nuclei in blue are breaking apart, indicating cell death.

Gold Outshines Platinum in Cancer Fight

Categories Health, Technology

Illustration of a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in the antibody, which together strongly amplify the effect of T cells on the cancer tumour.

New ‘3-in-1’ Antibody Shows Promise in Cancer Treatment

Categories Health

Nanotubes deliver mitochondria to T cells, supercharging the T cells to make them more effective in the fight against cancer. Image courtesy of Shiladitya Sengupta, BWH

Scientists Discover How to Recharge ‘Exhausted’ Cancer-Fighting Immune Cells

Categories Health

Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Glioblastoma is one of the most aggressive cancers, as illustrated by these brain scans from a patient with glioblastoma at initial diagnosis (left) and the same patient with a recurrent tumor (right).

New Drug Strategy Makes Aggressive Brain Cancer Visible to Immune System

Categories Brain & Behavior, Health

A caterpillar infected with Cordyceps militaris, the pretty orange fungus that produces Cordycepin.

Asian Caterpillar Fungus Reveals New Potential in Cancer Treatment

Categories Health, Life & Non-humans

Tertiary lymphoid structure.

Novel Immune Structures in Liver Tumors Point to Cancer Treatment Breakthrough

Categories Health

Corresponding author Dr. Evan Lien and first author Kelly Sokol in the lab at Van Andel Institute.

Study Shows Blocking Fat Access Makes Cancer Treatment More Effective

Categories Health

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