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Aging

When the protein STING (pink) is activated, the transcription factor TFEB (green) is shuttled into the nucleus where it stimulates the production of lysosomes

STING Protein Plays Dual Role in Cellular Health and Aging, Pitt Study Finds

Categories Health

stacked, frozen fish at a market

Fish Gut Bacteria Yield Promising Compounds for Anti-Aging Skincare

Categories Health, Life & Non-humans

Researchers investigated the function of PQBP3, a protein that was previously linked to certain neurodegenerative diseases, and unveiled its role in maintaining the integrity of the nuclear membrane. In senescent (aged) cells, PQBP3 concentration is decreased thereby promoting Lamin B1 degradation, and PQBP3 leaks from its typical place in the nucleolus to the cytosol, which in turn causes the nuclear membrane to get destabilized.

Protein Discovery Illuminates Link Between Aging and Brain Diseases

Categories Brain & Behavior

A griffon vulture — besties not pictured — in flight.

Like people, vultures have fewer friends as they age

Categories Earth, Energy & Environment, Life & Non-humans

Mitochondria release segments of mitochondrial DNA that can travel through pores of the nucleus and integrate into a cell's chromosomes (where the insertions are called NUMTs, for nuclear mitochochondrial segments). A new study has found that nuclear mitochondrial DNA insertion—once thought rare—happens in the human brain likely several times over during a person’s lifespan.

Mitochondria are flinging their DNA into our brain cells

Categories Brain & Behavior, Health

Reminiscent of a Halloween pumpkin, this collection of dots shows cells forming part of the thymus.

Unlocking the Secrets of Our Aging Immune System: New Insights into Thymus Decline

Categories Health

garbage dump

Cleaning up the aging brain: Scientists restore brain’s trash disposal system

Categories Brain & Behavior

Stochastic methylation clocks?

Categories Bloggers

middle aged man looking perplexed

Study Links Declining Sense of Purpose to Mild Cognitive Impairment

Categories Brain & Behavior, Health, Social Sciences

Man in his 50s with hands up

Stanford Study Reveals Major Molecular Shifts in Our 40s and 60s

Categories Health

Funeral by Funeral

Categories Bloggers

Older couple walking in a park

Groundbreaking Treatment Offers Hope for Human Longevity

Categories Health

eggs in a carton

Folate Restriction in Later Life May Promote Healthier Aging

Categories Brain & Behavior, Health

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