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University of Pittsburgh

(a) MRI shows electrode placement (SMA02, T11-T12) near the conus medullaris (yellow, below T12). Wireless stimulators targeted leg muscles (SMA03 example: 5mA/40Hz/400μs right, 5.5mA/40Hz/400μs left). (b) 3D motion capture and EMG recorded 7 leg muscles (ST, BF, VL, RP, RD, G, TA) during walking. (c) Study timeline. (d) Decreased EMG response with increasing SCS frequency (SMA01) indicates sensory-driven motor neuron recruitment. (e) Passive knee movement (SMA03) using a robotic system. Angle-dependent spinal reflexes (rectus femoris EMG shown) confirm sensory afferent activation by SCS. (Insets show reflexes at max extension/flexion).

Shocking the Spine Back to Life

Categories Health, Technology

Or Shemesh, Ph.D.

Surprising Protective Role of Tau Protein Against Herpes Virus in Alzheimer’s

Categories Brain & Behavior

Nanotubes deliver mitochondria to T cells, supercharging the T cells to make them more effective in the fight against cancer. Image courtesy of Shiladitya Sengupta, BWH

Scientists Discover How to Recharge ‘Exhausted’ Cancer-Fighting Immune Cells

Categories Health

Lipid deposits (green) in brain immune cells (red) from mice with Alzheimer’s-like disease all but disappear (right) after the mice are treated with an experimental drug. Researchers at Washington University School of Medicine in St. Louis have found that a form of cholesterol known as cholesteryl esters builds up in the brains of mice with Alzheimer’s-like disease, and that clearing out the cholesteryl esters helps prevent brain damage and behavioral changes.

Quality, not amount, of ‘good’ cholesterol contribute to first sign of Alzheimer’s in women

Categories Brain & Behavior, Health

When the protein STING (pink) is activated, the transcription factor TFEB (green) is shuttled into the nucleus where it stimulates the production of lysosomes

STING Protein Plays Dual Role in Cellular Health and Aging, Pitt Study Finds

Categories Health

Demo of app being used

Smartphone App Transforms Blood Pressure Monitoring for Underserved Communities

Categories Health, Technology

T Corona Borealis (TCrB)

A nova is coming: learn more about this stellar explosion

Categories Physics & Mathematics, Space

Vision of the proposed research for developing a self-powered, millifluidic lab-on-a-chip device to determine blood conductivity. a) Schematics and dimensions of the proposed device. The blood layer, copper electrodes, PTFE disc, and PMMA elements form a contact-separation mode TENG system. The blood sample is sandwiched between two PMMA layers and serves as one of the conductive layers. Any change in its electrical conductivity would theoretically change the voltage signal generated by the device. b) Operating principle of this blood-based TENG device. c) The 3D printed device and the type of voltage signal generated by it.

Novel blood-powered chip offers real-time health monitoring

Categories Health, Technology

red blood cells

Drug candidate may ‘unmask’ latent HIV-infected cells, mark them for destruction

Categories Health

Student memorizing information from a textbook

Study: Best way to memorize stuff? It depends…

Categories Brain & Behavior

Eggs, nuts and other sources of protein

Eating too much protein is bad for your arteries, and this amino acid is to blame

Categories Health

Thanos Tzounopoulos, Ph.D.

Scientists find biological mechanism of hearing loss caused by loud noise – and how to prevent it

Categories Brain & Behavior, Health

Angus W. Thomson, Ph.D., D.Sc., distinguished professor of immunology and surgery at the University of Pittsburgh and member of the Thomas E. Starzl Transplantation Institute

Trial results indicate potential for organ transplantation without long-term immunosuppression

Categories Health

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